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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50034352
Substrate
n/a
Meas. Tech.
ChEMBL_579 (CHEMBL615449)
Ki
62.0±n/a nM
Citation
 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives. J Med Chem 36:1069-83 (1993) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50034352
Synonyms:
(3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol | (3aS,9aR)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol | 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol | CHEMBL11066
Type:
Small organic molecule
Emp. Form.:
C15H21NO
Mol. Mass.:
231.3333
SMILES:
CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Structure:
Search PDB for entries with ligand similarity: