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Target
D(2) dopamine receptor
Ligand
BDBM50034338
Substrate
n/a
Meas. Tech.
ChEMBL_62551 (CHEMBL674063)
Ki
118±n/a nM
Citation
 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives. J Med Chem 36:1069-83 (1993) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50034338
Synonyms:
(3aS,9aR)-1-Cyclopropylmethyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol | 1-Cyclopropylmethyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol | CHEMBL11771
Type:
Small organic molecule
Emp. Form.:
C16H21NO
Mol. Mass.:
243.344
SMILES:
Oc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12
Structure:
Search PDB for entries with ligand similarity: