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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50368830
Substrate
n/a
Meas. Tech.
ChEMBL_157562 (CHEMBL763314)
Ki
22±n/a nM
Citation
 Thaisrivongs, S; Turner, SR; Strohbach, JW; TenBrink, RE; Tarpley, WG; McQuade, TJ; Heinrikson, RL; Tomasselli, AG; Hui, JO; Howe, WJ Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere. J Med Chem 36:941-52 (1993) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50368830
Synonyms:
CHEMBL1790518
Type:
Small organic molecule
Emp. Form.:
C34H56N4O5
Mol. Mass.:
600.8322
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)C1CCCCC1)C(=O)NCc1ccccn1
Structure:
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