Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50041663
Substrate
n/a
Meas. Tech.
ChEMBL_138761 (CHEMBL747847)
IC50
39000±n/a nM
Citation
 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F [L-Ala3]DPDPE: a new enkephalin analog with a unique opioid receptor activity profile. Further evidence of delta-opioid receptor multiplicity. J Med Chem 37:1572-7 (1994) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50041663
Synonyms:
2-Amino-N-(7-benzyl-4-dihydroxymethyl-10-hydroxymethyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-13-yl)-3-(4-hydroxy-phenyl)-propionamide | CHEMBL2372409
Type:
Small organic molecule
Emp. Form.:
C31H43N5O8S2
Mol. Mass.:
677.832
SMILES:
CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)O |r|
Structure:
Search PDB for entries with ligand similarity: