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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50038707
Substrate/Competitorn/a
Meas. Tech.ChEMBL_200981
Ki 0.050000±n/a nM
Citation Hudkins, RLMailman, RBDeHaven-Hudkins, DL Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds. J Med Chem37:1964-70 (1994) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Aging-associated gene 8 protein | SIG-1R | SR-BP | SR31747-binding protein | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Sigma 0 HUMAN::Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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BDBM50038707
NameBDBM50038707
Synonyms:1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(4-phenyl-piperidin-1-yl)-ethyl ester; hydrochloride | CHEMBL541284
TypeSmall organic molecule
Emp. Form.C25H30N2O4
Mol. Mass.422.5167
SMILES[O-][N+](=O)c1ccc(cc1)C1(CCCC1)C(=O)OCCN1CCC(CC1)c1ccccc1
Structure
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