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Target
Neutral alpha-glucosidase C
Ligand
BDBM50403869
Substrate
n/a
Meas. Tech.
ChEMBL_34407 (CHEMBL647805)
IC50
17000±n/a nM
Citation
 Asano, N; Oseki, K; Kizu, H; Matsui, K Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases. J Med Chem 37:3701-6 (1994) [PubMed]  Article 
Target
Name:
Neutral alpha-glucosidase C
Synonyms:
GANC_MOUSE | Ganc
Type:
PROTEIN
Mol. Mass.:
102002.29
Organism:
Mus musculus
Description:
ChEMBL_34410
Residue:
898
Sequence:
MEAAEKEEISVEDEAVDKTIFKDCGKIAFYRRQKQQLTKTTTYQALLGSVDTEQDSTRFQIISEATKIPLVAEVYGIEKDIFRLKINEETPLKPRLVCSGDTGSLILTNRKGDLKCHVSANPFKIDLLSKNEAVISINSLGQLYFEHLQVPHKQRATKGNGQNTPAATSQENQEDLGLWEEKFGKFVDVKANGPSSVGLDFSLHGFEHLYGIPQHAESHQLKNTRDGDAYRLYNLDVYGYQVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAVEYTLTQMGPAAAKPKVRCRTDVHWMSESGIIDVFLLTGPTPADVFKQYSYITGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKKRKLVVISDPHIKVDPDYTVYAQAKEQGFFVKNPEGGDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMHKSAVHYGDWEHRELHNIYGFYQQMATAEGLIQRSKGKERPFVLSRSFFAGSQKYGAVWTGDNKAEWSYLKISIPMLLTLSVSGISFCGADVGGFIGNPEAELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEYTQLIREAIRQRYALLPYLYSLFYHTHVSSQPVMRPLWVEYPDDLETFAVEDEYMLGSALLVHPVTDPQTATIDVFLPGSDEVWYDSKTFAYWKGGCTVKIPVTLDTIPVFQRGGSVVPVKTTVGTSTGWMADSPYELRVALSTQGSAVGELYLDDGHSFQYLHQNQFLYRKFLFCSSVLTNRCANEKGHYPSKCIVEQILVLGLKKKPSSVTTHLSDGRAQPAAFTYCAETSALRLEKLSLRIGEDWEVRVG
  
Inhibitor
Name:
BDBM50403869
Synonyms:
CHEMBL2115197
Type:
Small organic molecule
Emp. Form.:
C6H13NO2
Mol. Mass.:
131.1729
SMILES:
CC[C@H]1NC[C@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: