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Target
D(2) dopamine receptor
Ligand
BDBM50029322
Substrate
n/a
Meas. Tech.
ChEMBL_63038 (CHEMBL678341)
Ki
32±n/a nM
Citation
 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ N-aryl-N'-benzylpiperazines as potential antipsychotic agents. J Med Chem 38:4211-22 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50029322
Synonyms:
Butyl-{4-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-amine with malleic acid
Type:
Small organic molecule
Emp. Form.:
C25H37N3O
Mol. Mass.:
395.5808
SMILES:
CCCCNCc1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)cc1
Structure:
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