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Target
D(2) dopamine receptor
Ligand
BDBM50048238
Substrate
n/a
Meas. Tech.
ChEMBL_59154 (CHEMBL671035)
Ki
151±n/a nM
Citation
 Thurkauf, A; Yuan, J; Chen, X; Wasley, JW; Meade, R; Woodruff, KH; Huston, K; Ross, PC 1-Phenyl-3-(aminomethyl)pyrroles as potential antipsychotic agents. Synthesis and dopamine receptor binding. J Med Chem 38:4950-2 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DRD2 | DRD2_CHLAE | Dopamine D2 receptor
Type:
PROTEIN
Mol. Mass.:
50619.11
Organism:
Cercopithecus aethiops
Description:
ChEMBL_59156
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSKIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRSHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKNHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50048238
Synonyms:
4-(4-Chloro-phenyl)-1-(1-phenyl-1H-pyrrol-3-ylmethyl)-piperidin-4-ol | CHEMBL147003
Type:
Small organic molecule
Emp. Form.:
C22H23ClN2O
Mol. Mass.:
366.884
SMILES:
OC1(CCN(Cc2ccn(c2)-c2ccccc2)CC1)c1ccc(Cl)cc1
Structure:
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