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Target
Platelet-activating factor receptor
Ligand
BDBM50034220
Substrate
n/a
Meas. Tech.
ChEMBL_162891 (CHEMBL768221)
Temperature
310.15±n/a K
IC50
>200000±n/a nM
Comments
extracted
Citation
 Fos, E; Suesa, N; Borras, L; Lobato, C; Banfi, P; Gambetta, RA; Zunino, F; Mauleón, D; Carganico, G Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity. J Med Chem 38:1216-28 (1995) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50034220
Synonyms:
2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide | CHEMBL125 | MILTEFOSINE | [2-(Hexadecyloxy-hydroxy-phosphoryloxy)-ethyl]-trimethyl-ammonium | hexadecyl 2-(trimethyl-lambda~5~-azanyl)ethyl hydrogen phosphate | hexadecyl 2-(trimethylammonio)ethyl phosphate | hexadecyloxy-2-trimethylammonioethylphosphorate | hexadecylphosphocholine | hexadecylphosphocholine, miltefosine | n-hexadecylphosphocholine
Type:
Small organic molecule
Emp. Form.:
C21H46NO4P
Mol. Mass.:
407.568
SMILES:
CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C
Structure:
Search PDB for entries with ligand similarity: