Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50052025
Substrate
n/a
Meas. Tech.
ChEMBL_99835 (CHEMBL709864)
Ki
1±n/a nM
Citation
 Brooks, CD; Summers, JB Modulators of leukotriene biosynthesis and receptor activation. J Med Chem 39:2629-54 (1996) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50052025
Synonyms:
6-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroman-7-yloxy)-hexyl]-phenoxy}-hexanoic acid | CHEMBL86900 | Ro-25-4094
Type:
Small organic molecule
Emp. Form.:
C33H44O8
Mol. Mass.:
568.6977
SMILES:
CCCc1c(OCCCCCCc2cccc(OCCCCCC(O)=O)c2CCC(O)=O)ccc2C(=O)CCOc12
Structure:
Search PDB for entries with ligand similarity: