Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50006798
Substrate
n/a
Meas. Tech.
ChEMBL_98638 (CHEMBL711838)
IC50
23±n/a nM
Citation
 Brooks, CD; Summers, JB Modulators of leukotriene biosynthesis and receptor activation. J Med Chem 39:2629-54 (1996) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_HUMAN | CYSLT1 | CYSLTR1 | Cysteinyl leukotriene D4 receptor | Cysteinyl leukotriene receptor | Cysteinyl leukotriene receptor 1 | HG55 | HMTMF81 | LTD4 receptor | Leukotriene Cysteinyl 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38565.16
Organism:
Homo sapiens (Human)
Description:
Leukotriene Cysteinyl 1 CYSLTR1 HUMAN::Q9Y271
Residue:
337
Sequence:
MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
  
Inhibitor
Name:
BDBM50006798
Synonyms:
2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic acid | 2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic acid(SR2640) | CHEMBL18132 | cid_128355
Type:
Small organic molecule
Emp. Form.:
C23H18N2O3
Mol. Mass.:
370.4006
SMILES:
OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1
Structure:
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