Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50037382
Substrate
n/a
Meas. Tech.
ChEMBL_99834 (CHEMBL709863)
Ki
3.7±n/a nM
Citation
 Brooks, CD; Summers, JB Modulators of leukotriene biosynthesis and receptor activation. J Med Chem 39:2629-54 (1996) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50037382
Synonyms:
5-{2-(2-Carboxy-ethyl)-3-[(E)-6-(4-methoxy-phenyl)-hex-5-enyloxy]-phenoxy}-pentanoic acid | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-phenyl)-hex-5-enyloxy]-phenoxy}-pentanoic acid (ONO-4057) | CHEMBL422420 | ONO 4057 | ONO-4057
Type:
Small organic molecule
Emp. Form.:
C27H34O7
Mol. Mass.:
470.5547
SMILES:
COc1ccc(\C=C\CCCCOc2cccc(OCCCCC(O)=O)c2CCC(O)=O)cc1
Structure:
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