| Reaction Details |
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 | Report a problem with these data |
| Target | DOPAMINE |
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| Ligand | BDBM50054090 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58656 |
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| Ki | 1.8±n/a nM |
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| Citation |  Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Synthesis, resolution, and preliminary evaluation of trans-2-amino-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes and related derivatives as dopamine receptors ligands. J Med Chem39:4238-46 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DOPAMINE |
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| Name: | Dopamine receptors; D1 & D2 |
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| Synonyms: | D(1A) dopamine receptor | DOPAMINE D1 | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | DOPAMINE 0 RAT::P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50054090 |
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| Name | BDBM50054090 |
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| Synonyms: | (1R,2R)-2-Dipropylamino-1-phenyl-indan-5-ol | CHEMBL135735 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27NO |
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| Mol. Mass. | 309.4452 |
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| SMILES | CCCN(CCC)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 |
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| Structure | 
|
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| n/a |
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