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Target
P-selectin
Ligand
BDBM50408284
Substrate
n/a
Meas. Tech.
ChEMBL_200024 (CHEMBL810713)
IC50
100000±n/a nM
Citation
 Tsukida, T; Hiramatsu, Y; Tsujishita, H; Kiyoi, T; Yoshida, M; Kurokawa, K; Moriyama, H; Ohmoto, H; Wada, Y; Saito, T; Kondo, H Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides. J Med Chem 40:3534-41 (1997) [PubMed]  Article 
Target
Name:
P-selectin
Synonyms:
CD62 antigen-like family member P | CD_antigen=CD62P | GMP-140 | Granule membrane protein 140 | Grmp | LECAM3 | LYAM3_MOUSE | Leukocyte-endothelial cell adhesion molecule 3 | PADGEM | Selp
Type:
PROTEIN
Mol. Mass.:
83091.41
Organism:
Mus musculus
Description:
ChEMBL_200024
Residue:
768
Sequence:
MAGCPKGSWTPRLRSVILGGAQLIWFSALISELVNQKEVAAWTYNYSTKAYSWNNSRVFCRRHFTDLVAIQNKNEIAHLNDVIPFFNSYYWIGIRKINNKWTWVGTNKTLTEEAENWADNEPNNKKNNQDCVEIYIKSNSAPGKWNDEPCFKRKRALCYTASCQDMSCSNQGECIETIGSYTCSCYPGFYGPECEYVKECGKVNIPQHVLMNCSHPLGEFSFNSQCTFSCAEGYELDGPGELQCLASGIWTNNPPKCDAVQCQSLEAPPHGTMACMHPIAAFAYDSSCKFECQPGYRARGSNTLHCTGSGQWSEPLPTCEAIACEPPEIPIHGSMDCVPSTGTFGYNSSCTFLCAEGFVLKGNDAIQCADSGQWTAPAPFCEALQCPEFPVPSKAQVNCSDPFGTLTYQSVCSFSCDEGSLLVGASVIRCLATGHWNGAPPECQAVSCAPMLSPENGSMTCVQPLGNSTYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGTPPTCEAIKCPGIFAPEQGNLDCSHVHGEFGVGSICHFSCNEDFELLGSENVECTVSGRWSAPPPTCKGITSLPAPAVRCPALTTPGQGTMSCQHHLGSFGPNTTCYFGCKTGFTLRGANSLRCRASGQWTAVTPMCRAVKCSELHMDTAVAMNCSNPWGNFSYGSTCTFQCPEGQSLNGSVRATCREDGHWSDAMPTCQAGTLTIQEALTYLGGAVASTTGLAVGGTLLALLRKRLRKKDDGKCPLNPHSHLGTYGVFTNAAYDPTP
  
Inhibitor
Name:
BDBM50408284
Synonyms:
CHEMBL2029056
Type:
Small organic molecule
Emp. Form.:
C48H91O18S
Mol. Mass.:
988.291
SMILES:
CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](OS([O-])(=O)=O)[C@H]2O)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@H]1O |r|
Structure:
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