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Target
Cholecystokinin receptor type A
Ligand
BDBM50056454
Substrate
n/a
Meas. Tech.
ChEMBL_49725 (CHEMBL661967)
Ki
2293±n/a nM
Citation
 Blommaert, AG; Dhôtel, H; Ducos, B; Durieux, C; Goudreau, N; Bado, A; Garbay, C; Roques, BP Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor. J Med Chem 40:647-58 (1997) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50056454
Synonyms:
CHEMBL2371224 | N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(3R,13R)-3-(1H-indol-3-ylmethyl)-3-methyl-2,5,7-trioxo-1,4,8triaza-cyclotridecane-13-carbonyl]-amino}-succinamic acid
Type:
Small organic molecule
Emp. Form.:
C34H41N7O8
Mol. Mass.:
675.7314
SMILES:
C[C@]1(Cc2c[nH]c3ccccc23)NC(=O)CC(=O)NCCCC[C@@H](NC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure:
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