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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50408432
Substrate
n/a
Meas. Tech.
ChEMBL_34094 (CHEMBL649723)
IC50
4400±n/a nM
Citation
 Asano, N; Nishida, M; Kato, A; Kizu, H; Matsui, K; Shimada, Y; Itoh, T; Baba, M; Watson, AA; Nash, RJ; Lilley, PM; Watkin, DJ; Fleet, GW Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. J Med Chem 41:2565-71 (1998) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | FUCO_RAT | Fuca | Fuca1
Type:
PROTEIN
Mol. Mass.:
53482.81
Organism:
Rattus norvegicus
Description:
ChEMBL_990950
Residue:
462
Sequence:
MWDLKSEWWAVGFGLLLLLAASAQAGGLAPHHYTPDWPSLDSRPLPRWFDEAKFGLFVHWGVYSVPAWGSEWFWWHWQGEQSSAYVRFMKENYPPGFSYADFAPQFTARFFHPEEWADLFQAAGAKYVVLTAKHHEGFTNWPSAVSWNWNSKDVGPHRDLVGELGAAVRKRNIRYGLYHSLFEWFHPLYLLDKKNGLKTQHFVSTKTMPELYDLVNRYKPDLIWSDGEWECPDSYWNSTEFLAWLYNESPVKDQVVVNDRWGQNCSCRHGGYYNCEDKYRPHSLPDHKWEMCTSVDKASWGYRRDMSMSTIVDENEIIEELVQTISLGGNYLLNIGPNKDGVIVPIFQERLLAVGKWLQINGEAIYASKPWRVQSERNKTVVWYTTKDSAVYATFLHWPEDGVVNLQSPKMTSATKITMLGMEGELHWTQDPLEGVLITLPQLPPGTFPVESAWTLKLTKVN
  
Inhibitor
Name:
BDBM50408432
Synonyms:
CHEMBL2115215
Type:
Small organic molecule
Emp. Form.:
C7H15NO5
Mol. Mass.:
193.1977
SMILES:
OC[C@H]1N[C@@H](CO)[C@@H](O)[C@@H](O)[C@@H]1O
Structure:
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