Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50369495
Substrate
n/a
Meas. Tech.
ChEMBL_30291 (CHEMBL639461)
EC50
37000±n/a nM
Citation
 de Zwart, M; Kourounakis, A; Kooijman, H; Spek, AL; Link, R; von Frijtag Drabbe Künzel, JK; IJzerman, AP 5'-N-substituted carboxamidoadenosines as agonists for adenosine receptors. J Med Chem 42:1384-92 (1999) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50369495
Synonyms:
CHEMBL606095
Type:
Small organic molecule
Emp. Form.:
C13H18N6O4
Mol. Mass.:
322.3198
SMILES:
CC(C)NC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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