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Target
Melanocortin receptor 5
Ligand
BDBM50095646
Substrate
n/a
Meas. Tech.
ChEMBL_106518 (CHEMBL713022)
EC50
550±n/a nM
Citation
 Grieco, P; Balse, PM; Weinberg, D; MacNeil, T; Hruby, VJ D-Amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8) on human MC3 receptor selectivity. J Med Chem 43:4998-5002 (2001) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36612.92
Organism:
Homo sapiens (Human)
Description:
P33032
Residue:
325
Sequence:
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
  
Inhibitor
Name:
BDBM50095646
Synonyms:
CHEMBL410795 | H-DTyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH | H-Tyr-DVal-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH | H-Tyr-Val-DMet-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH | H-Tyr-Val-Met-Gly-DHis-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH | H-Tyr-Val-Met-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gly-OH | H-Tyr-Val-Met-Gly-His-Phe-Arg-DTrp-Asp-Arg-Phe-Gly-OH | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-DPhe-Gly-OH | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH( gama-melanocyte-stimulating hormone(MSH)) | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-DArg-Phe-Gly-OH | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-DAsp-Arg-Phe-Gly-OH | H-Tyr-Val-Met-Gly-His-Phe-DArg-Trp-Asp-Arg-Phe-Gly-OH
Type:
Small organic molecule
Emp. Form.:
C74H99N21O16S
Mol. Mass.:
1570.774
SMILES:
CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O
Structure:
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