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Target
Mu-type opioid receptor
Ligand
BDBM50021347
Substrate
n/a
Meas. Tech.
ChEMBL_148092 (CHEMBL751574)
Ki
0.020000±n/a nM
Citation
 Subramanian, G; Paterlini, MG; Portoghese, PS; Ferguson, DM Molecular docking reveals a novel binding site model for fentanyl at the mu-opioid receptor. J Med Chem 43:381-91 (2000) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50021347
Synonyms:
CHEMBL12391 | N-(3-Methyl-1-phenethyl-piperidin-4-yl)-N-phenyl-propionamide | N-(3-Methyl-1-phenethyl-piperidin-4-yl)-N-phenyl-propionamide((3R,4S)-cis-3-methylfentanyl)
Type:
Small organic molecule
Emp. Form.:
C23H30N2O
Mol. Mass.:
350.4971
SMILES:
CCC(=O)N([C@H]1CCN(CCc2ccccc2)C[C@H]1C)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: