Reaction Details Report a problem with these data
Target
2-oxoglutarate receptor 1
Ligand
BDBM50369939
Substrate
n/a
Meas. Tech.
ChEMBL_151406 (CHEMBL754752)
Ki
2000±n/a nM
Citation
 Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem 44:208-14 (2001) [PubMed]  Article 
Target
Name:
2-oxoglutarate receptor 1
Synonyms:
G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15
Type:
PROTEIN
Mol. Mass.:
38385.93
Organism:
Rattus norvegicus
Description:
ChEMBL_151406
Residue:
337
Sequence:
MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP
  
Inhibitor
Name:
BDBM50369939
Synonyms:
CHEMBL609774
Type:
Small organic molecule
Emp. Form.:
C20H26N6O4
Mol. Mass.:
414.4582
SMILES:
Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1C2CC3CC(C2)CC1C3 |r,wU:12.19,wD:15.18,13.15,TLB:19:20:22:25.26.24,THB:27:28:22:25.26.24,27:25:22:20.28.29,24:23:20:25.27.26,24:25:20:23.22.29,(17.28,-1.3,;17.3,-2.84,;18.64,-3.59,;18.64,-5.13,;17.3,-5.88,;15.98,-5.13,;14.54,-5.61,;13.66,-4.36,;14.54,-3.12,;15.98,-3.59,;13.52,-6.72,;12.25,-5.92,;11.07,-6.88,;11.6,-8.31,;10.68,-9.71,;13.14,-8.21,;14.19,-9.49,;9.58,-6.53,;9.14,-5.06,;8.52,-7.64,;7.07,-7.22,;5.81,-7.32,;4.51,-8.59,;3.26,-7.7,;1.79,-6.2,;2.3,-4.16,;2.87,-6.18,;4.43,-4.16,;5.81,-6.3,;4.59,-7.55,)|
Structure:
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