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TargetChymotrypsin
LigandBDBM87059
Substrate/Competitorn/a
Meas. Tech.ChEMBL_49619
Ki 9.360±n/a nM
Citation Akahoshi, FAshimori, ASakashita, HYoshimura, TEda, MImada, TNakajima, MMitsutomi, NKuwahara, SOhtsuka, TFukaya, CMiyazaki, MNakamura, N Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic difluoromethylene ketones as novel inhibitors of human chymase. J Med Chem44:1297-304 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chymotrypsin
Name:Chymotrypsin C
Synonyms:Caldecrin | Chymotrypsin C | Chymotrypsin-C
Type:Enzyme
Mol. Mass.:29487.98
Organism:Homo sapiens (Human)
Description:Q99895
Residue:268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV
VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR
RGCNTRKKPVVYTRVSAYIDWINEKMQL
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  Blast E-value cutoff:
BDBM87059
NameBDBM87059
Synonyms:CHEMBL247767 | Chymostatin
TypeSmall organic molecule
Emp. Form.C31H41N7O6
Mol. Mass.607.7005
SMILESCC(C)C[C@H](NC(=O)[C@@H](NC(=O)N[C@@H](Cc1ccccc1)C(O)=O)C1CCNC(N)=N1)C(=O)N[C@@H](Cc1ccccc1)C=O |c:30|
Structure
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