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Target
Vesicular glutamate transporter 3
Ligand
BDBM50113317
Substrate
n/a
Meas. Tech.
ChEMBL_213566 (CHEMBL816123)
Ki
190±n/a nM
Citation
 Carrigan, CN; Bartlett, RD; Esslinger, CS; Cybulski, KA; Tongcharoensirikul, P; Bridges, RJ; Thompson, CM Synthesis and in vitro pharmacology of substituted quinoline-2,4-dicarboxylic acids as inhibitors of vesicular glutamate transport. J Med Chem 45:2260-76 (2002) [PubMed]  Article 
Target
Name:
Vesicular glutamate transporter 3
Synonyms:
Slc17a8 | VGLU3_RAT | Vglut3
Type:
PROTEIN
Mol. Mass.:
64750.88
Organism:
Rattus norvegicus
Description:
ChEMBL_213568
Residue:
588
Sequence:
MPFNAFDTFKEKILKPGKEGVKNAVGDSLGILQRKLDGTNEEGDAIELSEEGRPVQTSRARAPVCDCSCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAVHPTISNEERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEEKCGIIDQDELAEETELNHEAFVSPRKKMSYGATTQNCEVQKTDRRQQRESAFEGEEPLSYQNEEDFSETS
  
Inhibitor
Name:
BDBM50113317
Synonyms:
Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naphthalene-1,3-disulfonic acid](Chicago Sky Blue) | CHEMBL311909
Type:
Small organic molecule
Emp. Form.:
C34H28N6O16S4
Mol. Mass.:
904.877
SMILES:
COc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S(O)(=O)=O)S(O)(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S(O)(=O)=O)S(O)(=O)=O)c(OC)c1 |w:9.10,34.36|
Structure:
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