Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50116458
Substrate
n/a
Meas. Tech.
ChEMBL_4798 (CHEMBL618343)
Ki
7000±n/a nM
Citation
 Müller, CE; Thorand, M; Qurishi, R; Diekmann, M; Jacobson, KA; Padgett, WL; Daly, JW Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. J Med Chem 45:3440-50 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_MOUSE | Adenosine A2b receptor | Adora2b
Type:
PROTEIN
Mol. Mass.:
36130.09
Organism:
Mus musculus
Description:
ChEMBL_11831
Residue:
332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPVTCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQRMELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
  
Inhibitor
Name:
BDBM50116458
Synonyms:
1-Methyl-2-phenyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one | CHEMBL117962
Type:
Small organic molecule
Emp. Form.:
C14H13N5O
Mol. Mass.:
267.2859
SMILES:
Cn1c(nc2NC(=O)N3CCN=C3c12)-c1ccccc1 |c:11|
Structure:
Search PDB for entries with ligand similarity: