Reaction Details Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM50108571
Substrate
n/a
Meas. Tech.
ChEMBL_45269 (CHEMBL658221)
Ki
13±n/a nM
Citation
 Masereel, B; Rolin, S; Abbate, F; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. J Med Chem 45:312-20 (2002) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4
Type:
Enzyme
Mol. Mass.:
35152.74
Organism:
Bos taurus (bovine)
Description:
Bovine isozyme, isolated from lung microsomes
Residue:
312
Sequence:
MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
  
Inhibitor
Name:
BDBM50108571
Synonyms:
2-Propyl-pentanoic acid 2-(2-sulfamoyl-benzothiazol-6-yloxy)-ethyl ester | CHEMBL108381
Type:
Small organic molecule
Emp. Form.:
C17H24N2O5S2
Mol. Mass.:
400.513
SMILES:
CCCC(CCC)C(=O)OCCOc1ccc2nc(sc2c1)S(N)(=O)=O
Structure:
Search PDB for entries with ligand similarity: