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Target
Methionine aminopeptidase 1
Ligand
BDBM50129648
Substrate
n/a
Meas. Tech.
ChEMBL_105134 (CHEMBL715018)
IC50
140±n/a nM
Citation
 Luo, QL; Li, JY; Liu, ZY; Chen, LL; Li, J; Qian, Z; Shen, Q; Li, Y; Lushington, GH; Ye, QZ; Nan, FJ Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae. J Med Chem 46:2631-40 (2003) [PubMed]  Article 
Target
Name:
Methionine aminopeptidase 1
Synonyms:
MAP 1 | MAP1 | MAP1_YEAST | MetAP 1 | Peptidase M 1
Type:
PROTEIN
Mol. Mass.:
43382.92
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_10701
Residue:
387
Sequence:
MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSPGGPRQRIK
  
Inhibitor
Name:
BDBM50129648
Synonyms:
3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxylic acid thiazol-2-ylamide | CHEMBL328350
Type:
Small organic molecule
Emp. Form.:
C15H16N4O2S
Mol. Mass.:
316.378
SMILES:
[#6]\[#6](-[#6])=[#6]/[#6]-[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Structure:
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