Reaction Details Report a problem with these data
Target
Fibroblast growth factor 1
Ligand
BDBM50143011
Substrate
n/a
Meas. Tech.
ChEMBL_70628 (CHEMBL678684)
Kd
740±n/a nM
Citation
 Bytheway, I; Cochran, S Validation of molecular docking calculations involving FGF-1 and FGF-2. J Med Chem 47:1683-93 (2004) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 1
Synonyms:
Acidic fibroblast growth factor | Beta-endothelial cell growth factor | ECGF-beta | FGF1 | FGF1_HUMAN | FGFA | Fibroblast growth factor 1 (FGF-1) | HBGF-1 | Heparin-binding growth factor 1 | aFGF
Type:
Protein
Mol. Mass.:
17461.01
Organism:
Homo sapiens (Human)
Description:
P05230
Residue:
155
Sequence:
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
  
Inhibitor
Name:
BDBM50143011
Synonyms:
(2-{[3,4-bis(sulfonatooxy)-2,5-bis[(sulfonatooxy)methyl]oxolan-2-yl]oxy}-6-(sulfonatomethyl)-4,5-bis(sulfonatooxy)oxan-3-yl)methanesulfonate | polysulfonated derivative
Type:
Small organic molecule
Emp. Form.:
C13H16O33S8
Mol. Mass.:
956.771
SMILES:
[O-]S(=O)(=O)CC1OC(OC2(COS([O-])(=O)=O)OC(COS([O-])(=O)=O)C(OS([O-])(=O)=O)C2OS([O-])(=O)=O)C(CS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O
Structure:
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