Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50160671
Substrate
n/a
Meas. Tech.
ChEMBL_302350 (CHEMBL828071)
Ki
4±n/a nM
Citation
 Vullo, D; Voipio, J; Innocenti, A; Rivera, C; Ranki, H; Scozzafava, A; Kaila, K; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett 15:971-6 (2005) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50160671
Synonyms:
Benzothiazole-2-sulfonic acid amide | CHEMBL168552
Type:
Small organic molecule
Emp. Form.:
C7H6N2O2S2
Mol. Mass.:
214.265
SMILES:
NS(=O)(=O)c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: