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Target
Mu-type opioid receptor
Ligand
BDBM50177898
Substrate
n/a
Meas. Tech.
ChEMBL_302766 (CHEMBL838830)
Ki
0.1±n/a nM
Citation
 Henriksen, G; Platzer, S; Hauser, A; Willoch, F; Berthele, A; Schwaiger, M; Wester, HJ 18F-labeled sufentanil for PET-imaging of mu-opioid receptors. Bioorg Med Chem Lett 15:1773-7 (2005) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50177898
Synonyms:
2-Fluoro-N-[4-methoxymethyl-1-(2-thiophen-2-yl-ethyl)-piperidin-4-yl]-N-phenyl-propionamide | CHEMBL196960 | N-[1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl-2-[(+/-)-[18F]fluoropropanamide
Type:
Small organic molecule
Emp. Form.:
C22H29FN2O2S
Mol. Mass.:
404.541
SMILES:
COCC1(CCN(CCc2cccs2)CC1)N(C(=O)C(C)F)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: