Reaction Details Report a problem with these data
Target
Somatostatin receptor type 3
Ligand
BDBM50159467
Substrate
n/a
Meas. Tech.
ChEMBL_306612 (CHEMBL829072)
IC50
>1000±n/a nM
Citation
 Rivier, JE; Kirby, DA; Erchegyi, J; Waser, B; Eltschinger, V; Cescato, R; Reubi, JC Somatostatin receptor 1 selective analogues: 3. Dicyclic peptides. J Med Chem 48:515-22 (2005) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50159467
Synonyms:
CHEMBL265839 | cyclo(7-11) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,Lys11]SRIF
Type:
Small organic molecule
Emp. Form.:
C76H104N16O18S2
Mol. Mass.:
1593.865
SMILES:
CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@@H](NC(=O)[C@H](NC2=O)[C@@H](C)O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)C(O)=O)cc1
Structure:
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