Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50179302
Substrate
n/a
Meas. Tech.
ChEMBL_325560 (CHEMBL860279)
Ki
>10000±n/a nM
Citation
 Novellino, E; Cosimelli, B; Ehlardo, M; Greco, G; Iadanza, M; Lavecchia, A; Rimoli, MG; Sala, A; Da Settimo, A; Primofiore, G; Da Settimo, F; Taliani, S; La Motta, C; Klotz, KN; Tuscano, D; Trincavelli, ML; Martini, C 2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching. J Med Chem 48:8253-60 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50179302
Synonyms:
2-(5-chloro-1H-benzo[d]imidazol-2-yl)quinoxaline | CHEMBL198673
Type:
Small organic molecule
Emp. Form.:
C15H9ClN4
Mol. Mass.:
280.712
SMILES:
Clc1ccc2nc([nH]c2c1)-c1cnc2ccccc2n1
Structure:
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