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Target
Adenosine receptor A2a
Ligand
BDBM21217
Substrate
n/a
Meas. Tech.
ChEMBL_325561 (CHEMBL860280)
Ki
833±n/a nM
Citation
 Novellino, E; Cosimelli, B; Ehlardo, M; Greco, G; Iadanza, M; Lavecchia, A; Rimoli, MG; Sala, A; Da Settimo, A; Primofiore, G; Da Settimo, F; Taliani, S; La Motta, C; Klotz, KN; Tuscano, D; Trincavelli, ML; Martini, C 2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching. J Med Chem 48:8253-60 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM21217
Synonyms:
2-(4-methyl-1H-1,3-benzodiazol-2-yl)quinoxaline | CHEMBL198779 | benzimidazole-quinoxaline, C3
Type:
Small organic molecule
Emp. Form.:
C16H12N4
Mol. Mass.:
260.2933
SMILES:
Cc1cccc2[nH]c(nc12)-c1cnc2ccccc2n1
Structure:
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