Target
Vasopressin V1a receptor
Ligand
BDBM50178191
Substrate
n/a
Meas. Tech.
ChEMBL_326539 (CHEMBL863357)
Ki
>10000±n/a nM
Citation
 Quattropani, ADorbais, JCovini, DPittet, PAColovray, VThomas, RJCoxhead, RHalazy, SScheer, AMissotten, MAyala, GBradshaw, CDe Raemy-Schenk, AMNichols, ACirillo, RTos, EGGiachetti, CGolzio, LMarinelli, PChurch, DJBarberis, CChollet, ASchwarz, MK Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists. J Med Chem 48:7882-905 (2005) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM50178191
Synonyms:
CHEMBL382515 | N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}[1,1'-biphenyl]-4-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C29H24N4O4S
Mol. Mass.:
524.59
SMILES:
Cc1ccc(cc1)N(CC(=O)N=Nc1c(O)[nH]c2ccccc12)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |w:11.11|
Structure:
Search PDB for entries with ligand similarity: