Reaction Details Report a problem with these data
Target
Solute carrier family 15 member 1
Ligand
BDBM50169129
Substrate
n/a
Meas. Tech.
ChEMBL_363882 (CHEMBL863213)
IC50
110000±n/a nM
Citation
 Vig, BS; Stouch, TR; Timoszyk, JK; Quan, Y; Wall, DA; Smith, RL; Faria, TN Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding. J Med Chem 49:3636-44 (2006) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 1
Synonyms:
Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1
Type:
PROTEIN
Mol. Mass.:
78818.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1488839
Residue:
708
Sequence:
MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
  
Inhibitor
Name:
BDBM50169129
Synonyms:
(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionic acid | CHEMBL316103 | Tyr-Ala
Type:
Small organic molecule
Emp. Form.:
C12H16N2O4
Mol. Mass.:
252.2664
SMILES:
C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: