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Target
Mu-type opioid receptor
Ligand
BDBM50370757
Substrate
n/a
Meas. Tech.
ChEMBL_392924 (CHEMBL870418)
Ki
11±n/a nM
Citation
 Wentland, MP; VanAlstine, M; Kucejko, R; Lou, R; Cohen, DJ; Parkhill, AL; Bidlack, JM Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. J Med Chem 49:5635-9 (2006) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50370757
Synonyms:
CHEMBL1162933
Type:
Small organic molecule
Emp. Form.:
C32H36N2O
Mol. Mass.:
464.641
SMILES:
CC1C2Cc3ccc(cc3C1(C)CCN2CC1CC1)C(=O)NCc1ccc(cc1)-c1ccccc1 |THB:0:1:3.4.9:14.12.13,5:4:1:14.12.13,8:9:1:14.12.13,15:14:1:3.4.9|
Structure:
Search PDB for entries with ligand similarity: