Target
Peptide deformylase
Ligand
BDBM50201888
Substrate
n/a
Meas. Tech.
ChEMBL_423229 (CHEMBL913367)
IC50
44±n/a nM
Citation
 Boularot, AGiglione, CPetit, SDuroc, YAlves de Sousa, RLarue, VCresteil, TDardel, FArtaud, IMeinnel, T Discovery and refinement of a new structural class of potent peptide deformylase inhibitors. J Med Chem 50:10-20 (2007) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50201888
Synonyms:
(1-hydroxycarbamoylmethyl-2-phenylethyl)carbamic acid tert-butyl ester | CHEMBL218819
Type:
Small organic molecule
Emp. Form.:
C15H22N2O4
Mol. Mass.:
294.3462
SMILES:
CC(C)(C)OC(=O)NC(CC(=O)NO)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: