Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50177155
Substrate
n/a
Meas. Tech.
ChEMBL_431067 (CHEMBL917772)
Ki
500±n/a nM
Citation
 Muccioli, GG; Wouters, J; Scriba, GK; Poppitz, W; Poupaert, JH; Lambert, DM 1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists. J Med Chem 48:7486-90 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50177155
Synonyms:
1-(bis(4-bromophenyl)methyl)-3-(4-bromophenyl)urea | CHEMBL427241
Type:
Small organic molecule
Emp. Form.:
C20H15Br3N2O
Mol. Mass.:
539.058
SMILES:
Brc1ccc(NC(=O)NC(c2ccc(Br)cc2)c2ccc(Br)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: