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Target
RmtA
Ligand
BDBM50210465
Substrate
n/a
Meas. Tech.
ChEMBL_434652 (CHEMBL914209)
IC50
8300±n/a nM
Citation
 Spannhoff, A; Heinke, R; Bauer, I; Trojer, P; Metzger, E; Gust, R; Schüle, R; Brosch, G; Sippl, W; Jung, M Target-based approach to inhibitors of histone arginine methyltransferases. J Med Chem 50:2319-25 (2007) [PubMed]  Article 
Target
Name:
RmtA
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
39351.26
Organism:
Emericella nidulans
Description:
ChEMBL_475539
Residue:
345
Sequence:
MSEIENSTITSSADRMVGMDHAEVRYFTSYDHHGIHEEMLKDDVRTRSYRDSIYQNRHIFKDKVVLDVGCGTGILSMFAAKAGAKHVIGVDMSSIIEKAREIVAVNGLADKITLLQGKMEEVQLPFPSVDIIISEWMGYFLLYESMLDTVLYAQDRYLVPGGKIFPDKATMYLAGIEDGEYKDDKIGFWDNVYGFDYSPMKEIALTEPLVDTVELKALVTDPCPIITFDLYTVTKEDLAFEVPYSLPVKRSDFVHAVIAWFDIEFGACHKPINFSTGPHAKYTHWKQTVFYLRDVLTVEEEESISGVLSNRPNDKNKRDLDINLTYKLETQDQTRFAEGGCFYRM
  
Inhibitor
Name:
BDBM50210465
Synonyms:
CHEMBL227725 | NSC-34238 | allantodapsone
Type:
Small organic molecule
Emp. Form.:
C17H14N4O6S
Mol. Mass.:
402.381
SMILES:
Nc1ccc(cc1)S(=O)(=O)c1ccc(NCN2C(=O)NC(=O)C(=O)C2=O)cc1
Structure:
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