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TargetEnoyl-acyl-carrier protein reductase
LigandBDBM50211929
Substrate/Competitorn/a
Meas. Tech.ChEMBL_436468
IC50>100000±n/a nM
Citation Kumar, GParasuraman, PSharma, SKBanerjee, TKarmodiya, KSurolia, NSurolia, A Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. J Med Chem50:2665-75 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-acyl-carrier protein reductase
Name:Enoyl-acyl-carrier protein reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:49770.86
Organism:Plasmodium falciparum
Description:ChEMBL_795989
Residue:432
Sequence:
MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50211929
NameBDBM50211929
Synonyms:CHEMBL390063 | methyl 6-(5-(4-ethylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoate
TypeSmall organic molecule
Emp. Form.C19H23NO3S2
Mol. Mass.377.521
SMILESCCc1ccc(\C=C2/SC(=S)N(CCCCCC(=O)OC)C2=O)cc1
Structure
n/a