Reaction Details Report a problem with these data
Target
IAG-nucleoside hydrolase
Ligand
BDBM50370996
Substrate
n/a
Meas. Tech.
ChEMBL_438446 (CHEMBL886424)
Ki
21000±n/a nM
Citation
 Goeminne, A; McNaughton, M; Bal, G; Surpateanu, G; Van der Veken, P; De Prol, S; Versées, W; Steyaert, J; Apers, S; Haemers, A; Augustyns, K 1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors. Bioorg Med Chem Lett 17:2523-6 (2007) [PubMed]  Article 
Target
Name:
IAG-nucleoside hydrolase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36316.77
Organism:
Trypanosoma vivax
Description:
ChEMBL_531315
Residue:
327
Sequence:
MAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTHCELLRDGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAEKYPLTFVARNPEAEFFLDMLLRSARAC
  
Inhibitor
Name:
BDBM50370996
Synonyms:
CHEMBL230908
Type:
Small organic molecule
Emp. Form.:
C15H19N3O4
Mol. Mass.:
305.3291
SMILES:
OC[C@H]1O[C@@H](CCn2cc(nn2)-c2ccccc2)[C@H](O)[C@@H]1O
Structure:
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