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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50374600
Substrate/Competitorn/a
Meas. Tech.ChEMBL_469590
Ki 0.12±n/a nM
Citation Mésangeau, CNarayanan, SGreen, AMShaikh, JKaushal, NViard, EXu, YTFishback, JAPoupaert, JHMatsumoto, RRMcCurdy, CR Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity. J Med Chem51:1482-6 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Opioid receptor | Sigma | Sigma opioid receptor | Sigma-1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50374600
NameBDBM50374600
Synonyms:CHEMBL272899
TypeSmall organic molecule
Emp. Form.C18H26N2OS
Mol. Mass.318.477
SMILESCCCc1ccc2n(CCN3CCCCCC3)c(=O)sc2c1
Structure
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