Reaction Details Report a problem with these data
Target
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal
Ligand
BDBM50241272
Substrate
n/a
Meas. Tech.
ChEMBL_543345 (CHEMBL1023015)
IC50
161000±n/a nM
Citation
 Freitas, RF; Prokopczyk, IM; Zottis, A; Oliva, G; Andricopulo, AD; Trevisan, MT; Vilegas, W; Silva, MG; Montanari, CA Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors. Bioorg Med Chem 17:2476-82 (2009) [PubMed]  Article 
Target
Name:
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal
Synonyms:
G3PG_TRYCR
Type:
PROTEIN
Mol. Mass.:
39070.68
Organism:
Trypanosoma cruzi
Description:
ChEMBL_973242
Residue:
359
Sequence:
MPIKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMNTDAEYFAYQMRYDTVHGKFKYEVTTTKSSPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAAEGHLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHVVSNASCTTNCLAPIVHVLVKEGFGVQTGLMTTIHSYTATQKTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQGKLTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRASKTYMKGILGYTDEELVSADFINDNRSSIYDSKATLQNNLPKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKDRSARL
  
Inhibitor
Name:
BDBM50241272
Synonyms:
(8E)-Anacardic acid | 6-(8'E-pentadecaenyl)salicylic acid | CHEMBL277156
Type:
Small organic molecule
Emp. Form.:
C22H34O3
Mol. Mass.:
346.5036
SMILES:
CCCCCC\C=C\CCCCCCCc1cccc(O)c1C(O)=O
Structure:
Search PDB for entries with ligand similarity: