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Target
P2Y purinoceptor 12
Ligand
BDBM50333877
Substrate
n/a
Meas. Tech.
ChEMBL_523462 (CHEMBL995340)
Ki
>10000±n/a nM
Citation
 Baqi, Y; Atzler, K; Köse, M; Glänzel, M; Müller, CE High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. J Med Chem 52:3784-93 (2009) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50333877
Synonyms:
1,8-Dihydroxy-3-methyl-anthraquinone | 1,8-Dihydroxy-3-methyl-anthraquinone(Chrysophanol) | 1,8-dihydroxy-3-methylanthracene-9,10-dione | CHEMBL443640 | chrysophanol
Type:
Small organic molecule
Emp. Form.:
C15H12O4
Mol. Mass.:
256.2534
SMILES:
Cc1cc(O)c2c(O)c3c(O)cccc3c(O)c2c1
Structure:
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