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Target
P2Y purinoceptor 2
Ligand
BDBM50118213
Substrate
n/a
Meas. Tech.
ChEMBL_587770 (CHEMBL1040421)
IC50
1510±n/a nM
Citation
 Sauer, R; El-Tayeb, A; Kaulich, M; Müller, CE Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists. Bioorg Med Chem 17:5071-9 (2009) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RY2_MOUSE | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | P2ru1 | P2ry2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42202.78
Organism:
Mus musculus
Description:
ChEMBL_587770
Residue:
373
Sequence:
MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
  
Inhibitor
Name:
BDBM50118213
Synonyms:
5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(tetrahydrogen triphosphate) | uridine 5'-triphosphoric acid
Type:
Small organic molecule
Emp. Form.:
C9H15N2O15P3
Mol. Mass.:
484.1411
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure:
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