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TargetIndoleamine 2,3-dioxygenase
LigandBDBM50303901
Substrate/Competitorn/a
Meas. Tech.ChEMBL_595174
IC50 10000±n/a nM
Citation Röhrig, UFAwad, LGrosdidier, ALarrieu, PStroobant, VColau, DCerundolo, VSimpson, AJVogel, PVan den Eynde, BJZoete, VMichielin, O Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem53:1172-89 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Indoleamine 2,3-dioxygenase
Name:Indoleamine 2,3-dioxygenase
Synonyms:IDO | IDO-1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine-pyrrole 2,3-dioxygenase
Type:Enzyme
Mol. Mass.:45330.80
Organism:Homo sapiens (Human)
Description:P14902
Residue:403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
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  Blast E-value cutoff:
BDBM50303901
NameBDBM50303901
Synonyms:1,4-Dihydroxynaphthalene | 1,4-Naphthohydroquinone | 1,4-naphthalenediol | CHEMBL206816 | Naphthalene-1,4-diol
TypeSmall organic molecule
Emp. Form.C10H8O2
Mol. Mass.160.1693
SMILESOc1ccc(O)c2ccccc12
Structure
n/a