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Target
Adenosine receptor A1
Ligand
BDBM50097431
Substrate
n/a
Meas. Tech.
ChEMBL_613353 (CHEMBL1074290)
Ki
76±n/a nM
Citation
 Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem 18:2195-203 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50097431
Synonyms:
4-Methoxy-N-(4-phenyl-thiazol-2-yl)-benzamide | 4-Methoxy-N-(4-phenyl-thiazol-2-yl)-benzamide(LUF5433) | 4-methoxy-N-(4-phenylthiazol-2-yl)benzamide | CHEMBL60156 | LUF-5433
Type:
Small organic molecule
Emp. Form.:
C17H14N2O2S
Mol. Mass.:
310.37
SMILES:
COc1ccc(cc1)C(=O)Nc1nc(cs1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: