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Target
D(2) dopamine receptor
Ligand
BDBM50322239
Substrate
n/a
Meas. Tech.
ChEMBL_642589 (CHEMBL1176478)
Ki
2.4±n/a nM
Citation
 Vangveravong, S; Taylor, M; Xu, J; Cui, J; Calvin, W; Babic, S; Luedtke, RR; Mach, RH Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626. Bioorg Med Chem 18:5291-300 (2010) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50322239
Synonyms:
1-(Benzofuran-3-ylmethyl)-4-(4-iodophenyl)piperidin-4-ol oxalate | CHEMBL1171249
Type:
Small organic molecule
Emp. Form.:
C20H20INO2
Mol. Mass.:
433.2828
SMILES:
OC1(CCN(Cc2coc3ccccc23)CC1)c1ccc(I)cc1
Structure:
Search PDB for entries with ligand similarity: