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Target
Transcriptional activator protein LasR
Ligand
BDBM50350705
Substrate
n/a
Meas. Tech.
ChEMBL_762761 (CHEMBL1816012)
IC50
13000±n/a nM
Citation
 McInnis, CE; Blackwell, HE Thiolactone modulators of quorum sensing revealed through library design and screening. Bioorg Med Chem 19:4820-8 (2011) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50350705
Synonyms:
CHEMBL1814827
Type:
Small organic molecule
Emp. Form.:
C10H15NO3S
Mol. Mass.:
229.296
SMILES:
CCCC(=O)CC(=O)N[C@H]1CCSC1=O |r|
Structure:
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