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Target
Death-associated protein kinase 3
Ligand
BDBM50380246
Substrate
n/a
Meas. Tech.
ChEMBL_813560 (CHEMBL2019669)
IC50
>40000±n/a nM
Citation
 Maryanoff, BE; McComsey, DF; Yabut, SC; Luci, DK; Jordan, AD; Masucci, JA; Jones, WJ; Abad, MC; Gibbs, AC; Petrounia, I Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site. ACS Med Chem Lett 2:538-543 (2011) [PubMed]  Article 
Target
Name:
Death-associated protein kinase 3
Synonyms:
DAP kinase 3 | DAP-like kinase | DAPK3 | DAPK3_HUMAN | ZIP-kinase | ZIPK
Type:
PROTEIN
Mol. Mass.:
52537.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586564
Residue:
454
Sequence:
MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALEQEKLQGVECGLR
  
Inhibitor
Name:
BDBM50380246
Synonyms:
CHEMBL2017214
Type:
Small organic molecule
Emp. Form.:
C21H26N8S
Mol. Mass.:
422.55
SMILES:
CSc1ccccc1Nc1nc(nc2c(NCC3CC3)ncnc12)N1CCNCC1
Structure:
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