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Target
Proto-oncogene tyrosine-protein kinase Src
Ligand
BDBM50383376
Substrate
n/a
Meas. Tech.
ChEMBL_818068 (CHEMBL2033710)
Ki
>10000±n/a nM
Citation
 Larson, ET; Ojo, KK; Murphy, RC; Johnson, SM; Zhang, Z; Kim, JE; Leibly, DJ; Fox, AM; Reid, MC; Dale, EJ; Perera, BG; Kim, J; Hewitt, SN; Hol, WG; Verlinde, CL; Fan, E; Van Voorhis, WC; Maly, DJ; Merritt, EA Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1. J Med Chem 55:2803-10 (2012) [PubMed]  Article 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src
Synonyms:
Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src
Type:
Protein
Mol. Mass.:
59838.60
Organism:
Homo sapiens (Human)
Description:
P12931
Residue:
536
Sequence:
MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM50383376
Synonyms:
CHEMBL2030558 | CHEMBL2069945 | US10544104, Compound 144 | US9765037, Compound 144
Type:
Small organic molecule
Emp. Form.:
C19H24N6O
Mol. Mass.:
352.4335
SMILES:
COc1ccc(cc1C)-c1nn(CC2CCNCC2)c2ncnc(N)c12
Structure:
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