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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50385680
Substrate
n/a
Meas. Tech.
ChEMBL_826078 (CHEMBL2045509)
Ki
6760.83±n/a nM
Citation
 Del Bello, F; Barocelli, E; Bertoni, S; Bonifazi, A; Camalli, M; Campi, G; Giannella, M; Matucci, R; Nesi, M; Pigini, M; Quaglia, W; Piergentili, A 1,4-dioxane, a suitable scaffold for the development of novel M3 muscarinic receptor antagonists. J Med Chem 55:1783-7 (2012) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1
Type:
Protein
Mol. Mass.:
51442.54
Organism:
Homo sapiens (Human)
Description:
P11229
Residue:
460
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50385680
Synonyms:
CHEMBL2042402
Type:
Small organic molecule
Emp. Form.:
C14H22NO2
Mol. Mass.:
236.3294
SMILES:
C[N+](C)(C)C[C@@H]1COC[C@@H](O1)c1ccccc1 |r|
Structure:
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